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National Cancer Data Base - Data Dictionary PUF 2016


PUF Data Item Name: 
Allowable values: 
0 - 3
Records the behavior of all cases reported to the NCDB. The fifth digit of the morphology code is the behavior code.
Analytic Note: 

This item is the product of the application of the conversion rules expressed in ICDO2-3_SEER.xls ( for cases diagnosed prior to 2001, which were originally coded according to ICD-O-2, and ICD-O-3 codes reported by facilities for cases diagnosed in 2001 or later.

Note: the xls file was modified from that available from the SEER web site – behavior code 1 associated with juvenile astrocytomas (9421) has been changed to 3 by agreement among North American registry standard setters, making it consistent with ICD-O-2.

Benign tumors or tumors of uncertain behavior (behavior codes 0, 1) are not reported to the NCDB except for the following sites: meninges (C70._), brain (C71._), spinal cord, cranial nerves, and other parts of central nervous system (C72._), pituitary gland (C75.1), craniopharyngeal duct (C75.2) and pineal gland (C75.3). These were not required to be reported until 2004.

Code Label Definition and Examples
0 Benign Benign
1 Borderline Uncertain whether benign or malignant
Borderline malignancy
Low malignant potential
Uncertain malignant potential
2 In situ and/or carcinoma in situ Adenocarcinoma in an adenomatous polyp with no invasion of stalk
Clark level 1 for melanoma (limited to epithelium)
Comedocarcinoma, noninfiltrating (C50.B)
2 Synonymous within situ Confined to epithelium
Hutchinson melanotic freckle, NOS (C44.B)
Intracystic, noninfiltrating
Intraepidermal, NOS
Intraepithelial, NOS
Involvement up to, but not including the basement membrane
Lentigo maligna (C44.B)
Lobular neoplasia (C50.B)
Lobular, noninfiltrating (C50.B)
No stromal involvement
Papillary, noninfiltrating or intraductal
Precancerous melanosis (C44.B)
Queyrat erythroplasia (C60.B)
3 Invasive Invasive or microinvasive